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Patriots vs. Bills Week 4 Odds & PredictionsThe Bills are a 74% favorite at home against the Patriots

New England Patriots at Buffalo Bills, Sunday, Oct 4, 1:00 PM ET. Prediction markets give the Bills a 74% chance to win (−279) and the Patriots 26% (+284). Kalshi, Polymarket US and Polymarket agree within a point. Kalshi's lines make it Bills −6.5, with 49.5 total points. The Bills are down 2 points this week on Kalshi. $519K has traded on the game in the last 24 hours.

Spread and total
BUF −6.5O/U 49.5

Kalshi's lines closest to a coin flip

NFL Week 4 · Sun, Oct 4 · 1:00 PM ET

Patriots vs. Bills moneyline odds

Upcoming

Prices to buy each team. Tap a price to open Kalshi, Polymarket US and Polymarket.

New England Patriots at Buffalo Bills: moneyline on Kalshi, Polymarket US and Polymarket, observed between Oct 4, 10:04 AM and 10:05 AM ET
TeamAverageKalshiPolymarket USPolymarketSources
Buffalo BillsHome · −27974%
$100 on Kalshi at the ask pays $135
Kalshi74¢Polymarket US74¢Polymarket74¢
New England PatriotsAway · +28426%
$100 on Kalshi at the ask pays $384
Kalshi26¢Lowest askPolymarket US26.3¢Polymarket27¢

Best prices to buy: Buffalo at 74¢ on Kalshi, Polymarket US and Polymarket; New England at 26¢ on Kalshi. Buying both costs exactly the $1 payout: no arbitrage. Traded in the past 24 hours: $307K on Kalshi, $194K on Polymarket and $19K on Polymarket US.

Kalshi: OpenPolymarket US: OpenPolymarket: Open Average is the mean of each venue's price for the outcome, where it lists one: the midpoint of Kalshi's bid and ask; Polymarket US's displayed price; the midpoint of Polymarket's bid and ask. Source: Kalshi / Polymarket US / Polymarket via DeFi Rate, observed between Oct 4, 10:04 AM and 10:05 AM ET.

Price history · Kalshi daily closeSep 22 – Oct 3

Over the past week on Kalshi, Buffalo lost 2 points, to 74%.

2030405060708026%74%
PatriotsBills

Source: Kalshi daily close via DeFi Rate, Sep 22 to Oct 3 (UTC days). A day without a close is left out.

Spread & total · Kalshi

Patriots vs. Bills spread and over/under

Kalshi prices a ladder of margins and totals. The highlighted row is closest to a coin flip.

Bills win by more than…

Spread ladder, Kalshi: the lines closest to a coin flip
Fair odds
5+ pts59%−141
6+ pts57%−130
7+ pts53%−111
8+ pts45%+125
10+ pts41%+147
All 27 spread lines

Spread ladder, Kalshi: every line
Fair odds
Patriots 2+ pts24%+326
Patriots 3+ pts22%+365
Patriots 4+ pts17%+506
Patriots 5+ pts16%+545
Patriots 6+ pts14%+641
Patriots 7+ pts13%+700
Patriots 8+ pts9.5%+953
Patriots 10+ pts7.5%+1233
Patriots 11+ pts6.5%+1438
Patriots 14+ pts4.5%+2122
Patriots 15+ pts3.5%+2757
Bills 2+ pts72%−251
Bills 3+ pts70%−228
Bills 4+ pts62%−160
Bills 5+ pts59%−141
Bills 6+ pts57%−130
Bills 7+ pts53%−111
Bills 8+ pts45%+125
Bills 10+ pts41%+147
Bills 11+ pts37%+174
Bills 14+ pts31%+228
Bills 15+ pts27%+277
Bills 17+ pts24%+326
Bills 18+ pts21%+388
Bills 21+ pts17%+506
Bills 24+ pts12%+770
Bills 28+ pts7.5%+1233
Total points over…

Total points ladder, Kalshi: the lines closest to a coin flip
Fair odds
47.559%−141
48.554%−115
49.551%−102
50.548%+111
51.544%+130
All 19 total lines

Total points ladder, Kalshi: every line
Fair odds
27.597%−2757
30.594%−1438
33.591%−953
36.585%−545
39.579%−376
42.572%−251
45.563%−167
46.561%−153
47.559%−141
48.554%−115
49.551%−102
50.548%+111
51.544%+130
54.537%+174
57.530%+239
60.522%+365
63.516%+545
66.512%+770
69.58.5%+1076

Open Chance is the midpoint of Kalshi's bid and ask. Fair odds are that chance as American odds, before fees. Source: Kalshi via DeFi Rate, observed between Oct 4, 9:58 AM and 10:05 AM ET.

Patriots vs. Bills stats

These figures cover the 2026 regular season through Week 2. The table compares each team’s record and per-game averages side by side.

Team statPatriotsBills
Record1-12-0
Points per game1538.5
Total yards per game302427.5
Passing yards per game193291
Rushing yards per game122.5144.5
First downs per game1727
Third-down conversion32.1%57.1%
Red-zone TD rate33.3%75.0%
Turnover differential−3+2
Sacks per game33.5
Time of possession30:4528:44

Stat leaders: Patriots — passing, Drake Maye (37/55, 386 YDS, 1 TD, 4 INT); rushing, Rhamondre Stevenson (24 CAR, 94 YDS); receiving, Romeo Doubs (3 REC, 96 YDS); Bills — passing, Josh Allen (40/60, 582 YDS, 5 TD); rushing, James Cook III (34 CAR, 192 YDS, 1 TD); receiving, Dalton Kincaid (12 REC, 225 YDS, 1 TD).

Source: ESPN team statistics. 2026 regular-season averages and leaders through Week 2; the section is refreshed as each week is completed.

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