Lions vs. Bills Week 2 Odds & Predictions
Thursday Night Football brings Detroit to Orchard Park for Buffalo's Week 2 home date on September 17 at 8:15 p.m. ET on Prime Video. Prediction markets currently make Buffalo the favorite at -154 (60.6% implied probability), while Detroit is priced at +151 (39.8%). The Lions vs. Bills board compares exact full-game winner prices from Kalshi and Polymarket, using volume-weighted pricing to show the consensus line, venue spreads and trading volume with hourly updates.
Top US prediction apps to trade on Week 2 Lions vs. Bills (available in 50 states)

Trade $10, Get $25
T&C’s apply.

Deposit $10 get a $50 trading bonus
Risk Disclaimer
Current Lions vs. Bills Odds: Buffalo Favorite to Win
Current probabilities across platforms with liquidity indicators
BUBuffalo
Vol —
Spread 1.0%
Agg
60.6%↑ +2.1%
P
61.5%
K
60.5%
U
60.5%
DEDetroit
Vol —
Spread 1.5%
Agg
39.8%↓ -1.2%
K
40.0%
U
40.0%
P
38.5%
| Outcome | Aggregated | Spread | Volume | Kalshi | Polymarket | Polymarket US |
|---|---|---|---|---|---|---|
BU Buffalo | 60.6% ↑ +2.1% | 1.0% | — |
Kalshi
60.5%
|
Polymarket
61.5%
|
Polymarket US
60.5%
|
DE Detroit | 39.8% ↓ -1.2% | 1.5% | — |
Kalshi
40.0%
|
Polymarket
38.5%
|
Polymarket US
40.0%
|
Week 2 line movement: Lions vs. Bills
Hover for details · Cursor-synced tooltips
Tap "Chart settings" to adjust the chart.
Chart settings
Arbitrage Scanner
Current cross-venue opportunities with fee calculations
Pairs (Venue-to-Venue)
| Outcome | Venue Pair | Leg A (Buy) | Leg B (Sell) | Gross Spread | After Fees | Actionable | Trade Now |
|---|---|---|---|---|---|---|---|
BU Buffalo |
Polymarket
→
Polymarket US | Buy @ P 39¢ | Sell @ U 60¢ | +21.00% | +21.00% |
Yes | |
DE Detroit |
Polymarket
→
Polymarket US | Buy @ P 39¢ | Sell @ U 39.5¢ | +0.50% | +0.50% |
No |
Outcome Diff
| Outcome A | Outcome B | Venue | A Odds | B Odds | Diff | Strategy | Trade Now |
|---|---|---|---|---|---|---|---|
BU Buffalo |
DE Detroit |
Polymarket | A 61.5% | B 38.5% | +23.00% | Buy spread | |
BU Buffalo |
DE Detroit |
Kalshi | A 60.5% | B 40.0% | +20.50% | Buy spread | |
BU Buffalo |
DE Detroit |
Polymarket US | A 60.5% | B 40.0% | +20.50% | Buy spread |
After-fee spreads apply the configured taker-fee model per side. Depth/slippage is not modeled in this scanner.
Methodology & Data Mapping
How we aggregate, normalize, and map cross-platform data
Default: Volume-Weighted Average Price (VWAP)
Weights each mapped market by its reported 24H USD volume at snapshot time. If volume is unavailable, we fall back to a simple average for that snapshot.
Use the VWAP/Simple toggle above the chart to switch aggregation views.
Kalshi: Official API (best bid/ask + last + 24H volume/liquidity when available).
Polymarket: Market data via their API (token prices + best bid/ask + 24H volume/liquidity when available).
Polymarket US: Gateway market data (yes/no prices + best bid/ask + market stats for volume/open interest where available).
Event data is updated hourly. Older history is downsampled.
Each event links one or more markets per provider. We normalize labels, map provider outcomes into a shared outcome list, and merge mapped markets where appropriate.
Cross-venue spread: Max–min difference across available venue probabilities for the same outcome.
Liquidity: Relative per-venue indicators based on provider liquidity fields (no depth/slippage modeling).
Arbitrage: Computed from best bid/ask when available (otherwise mid); after-fee spread applies the configured fee model only.
NFL Week 2 Odds: Daily Predictions and Lines
Trading in the Miami Dolphins vs. San Francisco 49ers matchup leads the early Week 2 board with $68,625 in Kalshi game composite volume. San Francisco is also the strongest favorite at 86% against Miami, while Philadelphia has moved from 66% to 76% against Tennessee since DeFi Rate’s first Week 2 snapshot on Aug. 31.
Kalshi Promo Code RATE: $25 Bonus for Week 1 Commanders vs. Eagles
Use the Kalshi promo code RATE for a $25 trading bonus before Commanders vs. Eagles. Philadelphia was a 70% favorite ahead of Sunday’s Week 1 matchup.
Kalshi Promo Code Rate: $25 Bonus for Broncos vs. Chiefs Monday Night Football
Unlock a $25 Kalshi bonus for Broncos vs. Chiefs Monday Night Football. Trade live prediction markets as this AFC West primetime showdown closes out the NFL Week 1 slate.
Polymarket Promo Code Rate: $50 Bonus for Cowboys vs. Giants SNF
It’s an NFC East battle to open this season’s Sunday Night Football slate. Polymarket pricing leans toward the Cowboys getting the win over the Giants in a game that’s set to attract significant trading volume.
Patriots-Seahawks Prediction Market Volume Jumps from $5.8M to $105.5M in 24 Hours
The first game of the 2026 regular season nearly quadrupled the Kalshi volume generated by last year’s opener, pushing reported volume across three operators above $111 million.
Prediction Market NFL Trading Volume Could Reach $57 Billion This Season
DeFi Rate projects Kalshi NFL trading volume will reach roughly $3.2 billion through Week 1 and $57 billion across the full 2026–27 season. The forecast reflects the sharp expansion in prediction-market participation and NFL contract inventory over the past year, while using last season’s week-by-week trading pattern to model how volume is likely to build across the season rather than extrapolating the current growth rate indefinitely.
















