NFL Week 2 Odds & Predictions

Trading in the Miami Dolphins vs. San Francisco 49ers matchup leads the early Week 2 board with $68,625 in Kalshi game composite volume. San Francisco is also the strongest favorite at 86% against Miami, while Philadelphia has moved from 66% to 76% against Tennessee since DeFi Rate’s first Week 2 snapshot on Aug. 31.

Use the Kalshi promo code RATE for a $25 trading bonus before Commanders vs. Eagles. Philadelphia was a 70% favorite ahead of Sunday’s Week 1 matchup.

Unlock a $25 Kalshi bonus for Broncos vs. Chiefs Monday Night Football. Trade live prediction markets as this AFC West primetime showdown closes out the NFL Week 1 slate.

It’s an NFC East battle to open this season’s Sunday Night Football slate. Polymarket pricing leans toward the Cowboys getting the win over the Giants in a game that’s set to attract significant trading volume.

The first game of the 2026 regular season nearly quadrupled the Kalshi volume generated by last year’s opener, pushing reported volume across three operators above $111 million.

DeFi Rate projects Kalshi NFL trading volume will reach roughly $3.2 billion through Week 1 and $57 billion across the full 2026–27 season. The forecast reflects the sharp expansion in prediction-market participation and NFL contract inventory over the past year, while using last season’s week-by-week trading pattern to model how volume is likely to build across the season rather than extrapolating the current growth rate indefinitely.